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Can Depression Cause Brain Damage

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The Brain’s Impact On Depression

Does Depression Cause Permanent Brain Damage?

Popular lore has it that emotions reside in the heart. Science, though, tracks the seat of your emotions to the brain. Certain areas of the brain help regulate mood. Researchers believe that more important than levels of specific brain chemicals nerve cell connections, nerve cell growth, and the functioning of nerve circuits have a major impact on depression. Still, their understanding of the neurological underpinnings of mood is incomplete.

Can The Brain Repair Itself After Brain Damage

It is said that major wounds cant heal without scarring. When a brain is damaged, medical help can reduce or minimize, yet even recover the effects but to some extent, sometimes you are left with disabilities that persist for the rest of your life. A brain may be able to rewire or reorganize itself after an injury, improving and adapting to external stimuli that may be the cause of the disrupted networks, this process is known as neuroplasticity.

Keys To Managing Depression Or Anxiety Triggered By A Tbi

For TBI victims whose injuries or symptoms seem mild, they may be able to manage episodes of depression and anxiety through basic self-care techniques such as exercise, eating right, and mindfulness practices. However, since victims of head injuries often struggle with physical injuries and/or chemical imbalances, these strategies may not be enough to help them cope, and they may need more help. Common treatment options include:

Psychotherapy and counseling. Many TBI victims are able to manage their anxiety and depression with the help of counseling. Techniques like cognitive behavioral therapy and dialectical behavior therapy have proven quite useful in helping TBI victims cope with and contextualize their feelings. Some therapists also use innovations like biofeedback to help patients identify and retrain their responses.

Medication. In some cases, the best way to provide relief to head injury victims and restore some quality of life is through the use of antidepressant medications which help balance the brain chemicals that trigger anxiety and depression. Because antidepressants are powerful psychotropic drugs that can deeply affect mood and logic, this path requires constant monitoring and supervision to make sure the right drugs are administered in the right dosages, so the patient truly benefits from them.

Elizabeth Denslow, OTR/L Flint Rehab

To help you understand emotional problems after traumatic brain injury, this article will discuss:

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Glutamate And Neuroprotection: Therapeutic Targets

Glutamate neurotransmission is controlled by a complex system of pre- and postsynaptic receptors, including ionotropic and metabotropic subtypes. In addition, regulation of tropic factor signaling cascades, including extracellular signal-related kinase , Akt, and cAMP response element binding can serve as neuroprotective targets for excitoxicity. There is also evidence that chronic ADT regulates the phosphorylation, trafficking, and expression of glutamate receptors, providing further evidence that the actions of ADT involves this neurotransmitter system. These topics have been extensively covered by a number of recent reviews.121,123,136,137 A brief discussion of the major glutamatergic targets will be discussed here.

Allosteric AMPA receptor potentiator agents make up another interesting group of drugs. These agents do not directly stimulate AMPA receptors, but slow the inactivation or desensitation of the receptors. The idea of using drugs that enhance AMPA receptor function would appear to be counterintuitive given the possibility of an overactive glutamate system. However, preclinical studies of these agents, which were first developed for enhancing cognition, demonstrate positive antidepressant-like effects in rodent models of depression.123,146

How Do Anxiety Disorders Affect Children

Does depression cause permanent brain damage? I

Its normal for children to feel some amount of anxiety, worry or fear at certain points. For example, a child may feel scared of a thunderstorm or barking dog. A teenager might get anxious about an upcoming test or school dance.

But sometimes, children approach these situations with overwhelming dread or they cant stop thinking about all the fears tied to one of these events. It may seem that none of your comforts help. These children often get stuck on their worries. They have a hard time doing their daily activities, like going to school, playing and falling asleep. Theyre extremely reluctant to try something new.

When thinking about your childs anxiety levels, getting stuck is key. It separates the regular worries of childhood from an anxiety disorder that needs professional help. If the anxiety or worry interferes with your childs ability to function, it may be time to seek help

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Early Losses And Trauma

Certain events can have lasting physical, as well as emotional, consequences. Researchers have found that early losses and emotional trauma may leave individuals more vulnerable to depression later in life.

Profound early losses, such as the death of a parent or the withdrawal of a loved one’s affection, may resonate throughout life, eventually expressing themselves as depression. When an individual is unaware of the wellspring of his or her illness, he or she can’t easily move past the depression. Moreover, unless the person gains a conscious understanding of the source of the condition, later losses or disappointments may trigger its return.

Traumas may also be indelibly etched on the psyche. A small but intriguing study in the Journal of the American Medical Association showed that women who were abused physically or sexually as children had more extreme stress responses than women who had not been abused. The women had higher levels of the stress hormones ACTH and cortisol, and their hearts beat faster when they performed stressful tasks, such as working out mathematical equations or speaking in front of an audience.

What Is An Anxiety Disorder

An anxiety disorder is a type of mental health condition. If you have an anxiety disorder, you may respond to certain things and situations with fear and dread. You may also experience physical signs of anxiety, such as a pounding heart and sweating.

Its normal to have some anxiety. You may feel anxious or nervous if you have to tackle a problem at work, go to an interview, take a test or make an important decision. And anxiety can even be beneficial. For example, anxiety helps us notice dangerous situations and focuses our attention, so we stay safe.

But an anxiety disorder goes beyond the regular nervousness and slight fear you may feel from time to time. An anxiety disorder happens when:

  • Anxiety interferes with your ability to function.
  • You often overreact when something triggers your emotions.
  • You cant control your responses to situations.

Anxiety disorders can make it difficult to get through the day. Fortunately, there are several effective treatments for anxiety disorders.

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What Causes Depression After Tbi

Many different factors contribute to depression after TBI, and these vary a great deal from person to person.

  • Physical changes in the brain due to injury. Depression may result from injury to the areas of the brain that control emotions. Changes in the levels of certain natural chemicals in the brain, called neurotransmitters, can cause depression.
  • Emotional response to injury. Depression can also arise as a person struggles to adjust to temporary or lasting disability, losses or role changes within the family and society.
  • Factors unrelated to injury.Some people have a higher risk for depression due to inherited genes, personal or family history, and other influences that were present before the brain injury.

Size Matters When It Comes To Your Hippocampus

Depression Can Cause Memory Loss and Difficulty Concentrating

In a study published in Molecular Psychiatry, researchers have found that when people encounter repeated bouts of depression, their hippocampus shows clear, physical shrinkage. The hippocampus, which is the part of the brain responsible for forming memories, also helps in developing healthy emotional behaviors.

Researchers began looking at the hippocampus because there was speculation as to whether a smaller hippocampus would lead to depression symptoms.

At the Brain and Mind Research Institute, researcher Ian Hickey built and cross-referenced a 9,000-person brain scan library. When comparing the healthy control brains to those that had experienced regular episodes of depression, he could reasonably conclude that depression actually does tangible, physical damage to the brain.

Further, when the subjects had started experiencing depression before the age of 21, their physical changes were most obvious.

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Increased Or Decreased Sexual Appetite

Its pretty common for patients with a history of brain injury to express loss or increased interest in sex. Thats why its crucial to show constant support and affection to the affected individual. Avoid pressuring your spouse or partner as much as possible. Also, try to set limitations to help manage each others expectations.

More often than not, these behavioral problems present challenges to both the carer and patient. In addition, it leads to increased difficulty in achieving recovery and reintegrating into society.

If you have a hard time coping with these, we suggest consulting with a behavioral therapist or a neuropsychologist. They can teach you strategies like breathing exercises or redirecting negative thoughts.

Structural And Functional Alterations Of The Brain Areas Involved In Depression

Research suggests that some people suffer from depression because their brain secretes too little neurotransmitter. Neurotransmitters are chemicals that brain cells use to communicate with each other and are believed to play a very important role in regulating mood.

The neurotransmitter deficit can be due to a chemical imbalance in the brain, but also to environmental factors such as diet and stress. Biochemical depression is treated with medication, psychotherapy, or a combination of both.

The causes of depression, it must be said, are not yet known for sure. It is known that different chemicals can contribute to depression, as we have seen in the previous section. Now it is also known how depression changes the brain:

Various investigations through imaging studies in patients with major depressive disorder have implicated structural alterations in various brain areas, including the hippocampus, the amygdala, and the dorsal lateral and ventral prefrontal cortex, with variable results.

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Physical Effects Of Depression On Brain

Depression is primarily known for the sadness it causes and all the non-physical symptoms including guilt, irritability, feelings of hopelessness, and trouble focusing or concentrating on tasks. Nevertheless, depression is a mental illness but it also causes physical symptoms. The physical symptoms caused by depression can also affect brain functioning. These physical symptoms include

A Long Road To Understanding Depression

Common Causes of Traumatic Brain Injury

For years and years, doctors and researchers assumed that depression stemmed from an abnormality within these neurotransmitters, particularly serotonin or norepinephrine. But over time, these two neurotransmitters did not seem to account for the symptoms associated with major depression. As a result, doctors began to look elsewhere.

The search proved fruitful. There are chemical messengers, which include glutamate and GABA, between the nerve cells in the higher centers of the brain involved in regulating mood and emotion, says John Krystal, MD, chair of Yales Department of Psychiatry, noting that these may be alternative causes for the symptoms of depression.

These two are the brains most common neurotransmitters. They regulate how the brain changes and develops over a lifetime. When a person experiences chronic stress and anxiety, some of these connections between nerve cells break apart. As a result, communication between the affected cells becomes noisy, according to Dr. Krystal. And its this noise, along with the overall loss of connections, that many believe contribute to the biology of depression.

There are clear differences between a healthy brain and a depressed brain, Dr. Katz says. And the exciting thing is, when you treat that depression effectively, the brain goes back to looking like a healthy brain.

In this video, Drs. Katz and Krystal explain how depression affects the brain.

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Physical Symptoms Of Anxiety

Anxiety may be taking place in your mind, but the side effects can certainly manifest in a physical way. While there are lots of physical side effects that can pop up, these are the most common.

General anxiety may include one or more of these symptoms,however, panic attacks often include many of them at once:

  • Restlessness

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Can Pba Go Away On Its Own

There’s no cure for PBA, but that doesn’t mean you have to live with uncontrolled crying or laughter for the rest of your life. Sometimes the symptoms will improve or go away once you treat the condition that caused your PBA. Medications can reduce the number of PBA episodes you have, or make them less intense.

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Why Is Untreated Depression Considered To Be A Disability

In addition, men with untreated depression may take dangerous risks such as reckless driving and having unsafe sex. Men are not aware that physical symptoms, such as headaches, digestive disorders and chronic pain, can be symptoms of depression. Why is untreated depression considered to be a disability?

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Learn More About Neulife One Of The Best Brain Injury Residential Facilities

Depression: Untreated depression can cause brain inflammation, study finds – TomoNews

NeuLife is a Residential Post-Acute Rehab facility specializing in traumatic brain injury rehabilitation, neurological disorder rehab and more. Its program includes physical medicine and rehabilitation, medical management, psychiatric and neuropsychological services, physical, occupational, speech and cognitive therapies, behavioral, dietary, and vocational counseling, and more.

Beautifully situated on 43 acres in Mount Dora, Florida, its inpatient rehab facility comprises over 60,000 square feet and contains 54 private rooms or suites.

For more information about NeuLife Rehabilitation Services, please give us a call at 800.626.3876, or visit our website. You can also make a referral or schedule a tour!

The material contained on this site is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE, and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions or concerns you may have regarding your health.

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Can Anxiety Damage The Brain

Can anxiety ruin your brain?

Summary: Pathological anxiety and chronic stress lead to structural degeneration and impaired functioning of the hippocampus and the PFC, which may account for the increased risk of developing neuropsychiatric disorders, including depression and dementia.

Does long term anxiety effects brain?

When youre anxious, your body is under a lot of stress. Stress shrinks the hippocampus, the part of the brain that processes long-term and contextual memory. When the hippocampus shrinks, it may become more difficult for your brain to hold onto memories.

Can brain heal itself from anxiety?

Scientists now know that the brain has an amazing ability to change and heal itself in response to mental experience. This phenomenon, known as neuroplasticity, is considered to be one of the most important developments in modern science for our understanding of the brain.

Overcome Mental Illness At Agape Treatment Center

At the Agape Behavioral Healthcare Network, we take mental health issues of all varieties very seriously and provide a safe, nurturing environment where one can learn about the disorders plaguing them from an emotionally unstable life.

Our licensed mental health clinicians will fully assess an individual that seems, feels, or has been previously diagnosed with a mental health disorder and meet them exactly where they are in life.

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What Stress And Anxiety Do To The Brain Over Time

This survival response is helpful and necessary when we encounter a real threat, but in excess, can cause long-term damage to our bodies. The effects of chronic stress have been linked to a weakened immune system, weight gain, and heart disease, among other issues.

But new research is finding a possible correlation between prolonged stress and anxiety, and structural degeneration of the hippocampus,

and impaired functioning of the prefrontal cortex. This means that the wear and tear caused to the brain by chronic stress or anxiety could be tied to an increased risk of depression and dementia.

The good news is that some of the damage incurred from chronic stress and anxiety is not completely irreversible, according to some experts. It was long believed that once a brain lost volume, it was gone forever, but we now know thats not entirely true. Our brains are plastic, meaning theyre capable of change. This plasticity allows our brains some degree of regrowth and regeneration.

The best way, however, to protect your brain and body from the effects of chronic stress and anxiety is to find a way to manage it before it begins to affect your health. Luckily, there are many different options for managing these conditions.

If youd like to learn more about Neuropeak Pros remote brain training programs, give us a call at .

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Neuroprotective And Neurotrophic Effects Of Exercise

New Research Shows Depression Causes Brain Damage, Not The Other Way Around

Exercise is reported to increase the expression of neurotrophic/growth factors, including BDNF, VEGF, FGF2, and IGF-1.111,114117 In addition, exercise increases neurogenesis in the adult hippocampus, an effect that is dependent on increased expression of IGF-1 and VEGF.111,114 IGF-1 has also been shown to underlie the neuroprotective effects of exercise against different types of brain insults.118 In addition to the regulation of these growth factors, exercise has also been shown to influence other neuroprotective mechanisms.119 These positive, neuroprotective actions make exercise one of the key behavioral factors for protecting, or even reversing the damage that can be caused by environmental, physical, and psychological stressors, and even the susceptibility resulting from genetic vulnerabilities .

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Why Is Getting Treatment So Important:

Some brain injuries are obvious due to the visible injuries. Others are more subtle. There are no outward signs of bloody wounds, but the brain can be severely injured. In either case, its imperative the injury be immediately diagnosed, and that treatment of the wounds and injury begins. This treatment can help to improve the patients physical and mental well being. It also means that any early signs of depression or anxiety are spotted and that the treatment of those symptoms can begin as well.

Too often when depression and anxiety arent identified early then treatment doesnt begin until a crisis point is reached. Self-medication with drugs and alcohol is a real risk.

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