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Can Lisinopril Cause Memory Loss

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Immediate Short Term Memory Loss

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Prevent Memory Loss Aging

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Anxiety And Insomnia Medications

Benzodiazepines, a class of medications used to treat anxiety or insomnia, comprise another group that has been linked with cognitive difficulties. Although these medications are truly a blessing for some individuals immobilized by anxiety, their use can be accompanied by sedation and mental slowing. A recent study even suggested that prolonged use of benzodiazepines might be a risk factor for later dementia, although experts have questioned the significance of this finding and clinicians continue to prescribe anti-anxiety medications such as lorazepam or sleeping pills such as temazepam and consider them very beneficial when used properly.

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What You Can Do Next

Youve read this list. Are any of these medications youre taking? If so, talk to your doctor if you believe theyre affecting your memory.

Get your doctor to work with you to find better options different prescriptions and/or healthy lifestyle choices instead.

If you are taking more than one medication, the chance of negative interactions goes up exponentially. Learn more about the problems of mixing medications in Protect Your Brain from the Perils of Polypharmacy.

Meanwhile, continue to use the lifestyle advice you find here on our website. Even if you have to stay on the medication, you can lessen the load on your brain by taking proactive steps such as eating a healthy diet, exercising, and taking the right supplements. Give your brain the healthiest possible environment to stay mentally sharp as long as you can.

This list was assembled by Richard C. Mohs, Ph.D., former vice chairman of the Department of Psychiatry at the Mount Sinai School of Medicine.

About the author:

Deane Alban holds a bachelors degree in biology and has taught and written on a wide variety of natural health topics for over 20 years. Her current focus is helping people overcome brain fog, senior moments, and other signs of mental decline now, and preventing Alzheimers and dementia in the future.

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Lisinopril Side Effects Hair Loss / 30 Causes Of Hair Loss ...
Chronic Inflammation Decoded

We discussed better options for controlling Madelines blood pressure, and she was relieved to learn that making a few lifestyle changes and taking appropriate supplements could make a big difference. I also encouraged her to start taking 500 mg of curcumin and 3 grams of omega-3 EFAs every day. And just eight weeks after Madeline took her last Metoprolol, she returned to my office in a much better state than she had been during the first visit.

I had convinced myself that I had early-onset Alzheimers. I really did not think that one medicine was responsible for my memory problems, but I was wrong! she told me. My memory gets better every day. Its still not as sharp as it was, but I think it will be eventually. From now on, Im not taking any prescription medication until I read about the side effects and look into alternatives.

The last time I spoke to Madeline during her annual physical, she was no longer worried about early retirement or memory issues. In fact, she was preparing to teach a course at one of the area law schools and volunteering with a literacy program.

Now that I dont have to read everything fourteen times to remember it, Ive got time to work in the community and volunteer for things that are important to me. And to think I was ready to give up! The difference youve made in my life is something Ill never forget.

August 16, 2018Originally Published: July 2, 2013

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It’s Not Dementia It’s Your Heart Medication: Cholesterol Drugs And Memory

Why cholesterol drugs might affect memory

ONE DAY IN 1999, Duane Graveline, then a 68-year-old former NASA astronaut, returned home from his morning walk in Merritt Island, Fla., and could not remember where he was. His wife stepped outside, and he greeted her as a stranger. When Gravelines memory returned some six hours later in the hospital, he racked his brain to figure out what might have caused this terrifying bout of amnesia. Only one thing came to mind: he had recently started taking the statin drug Lipitor.

Cholesterol-lowering statins such as Lipitor, Crestor and Zocor are the most widely prescribed medications in the world, and they are credited with saving the lives of many heart disease patients. But recently a small number of users have voiced concerns that the drugs elicit unexpected cognitive side effects, such as memory loss, fuzzy thinking and learning difficulties. Hundreds of people have registered complaints with MedWatch, the U.S. Food and Drug Administrations adverse drug reaction database, but few studies have been done and the results are inconclusive. Nevertheless, many experts are starting to believe that a small percentage of the population is at risk, and they are calling for increased public awareness of the possible cognitive side effects of statinssymptoms that may be misdiagnosed as dementia in the aging patients who take them.

doi:10.1038/scientificamericanmind0910-14

How High Blood Pressure Can Affect Thinking Skills

High blood pressure leads to brain changes that are similar to the results of a stroke. Sometimes these changes are called silent strokes because they dont always cause symptoms at the time.

High blood pressure may also damage tiny arteries that feed white matterthe wire-like cells that carry information from one area of the brain to another.

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Metoprolol & Memory Loss My Patients Story

After more than 20 years as a judge, Madeline came to me distraught and miserable.

I dont know whats wrong with me, but I cant remember anything, she confided in my office. I sit in court all day, listening to testimony, and by that evening Ive forgotten all of it and have to review the entire days conversations. And even then, its a struggle to recall what I just read! Im thinking of taking early retirement because I cant perform the duties of the job any longer.

Clearly, early retirement was not something Madeline wanted to do. But she was in tears as she described how hard she had to work to remember the various points of each case. Having seen this frustration in quite a few older patients, I understood how difficult it is to experience memory failure. But I also knew that there was hope for Madeline. The key was finding out why she was having memory problems

It didnt take long! In fact, as soon as I asked which medications her previous doctor had prescribed, the answer was right there Madelines blood pressure medication, Metoprolol, has been linked to memory loss, confusion, and insomnia, among other things.

Risks Should Be Carefully Considered

Healthy Eating : Lisinopril Medicine Side Effects

To assess the strength of anticholinergic drugs and how often the participants took them, the team looked at available information about prescriptions over a period of 10 years.

However, they note that this is an observational study, so they cannot confirm whether the drugs are directly responsible for the increased risk of dementia.

The researchers add that doctors may have prescribed some of these drugs to their patients precisely for the treatment of very early dementia symptoms.

Nevertheless, Prof. Coupland argues that the study adds further evidence of the potential risks associated with strong anticholinergic drugs, particularly antidepressants, bladder antimuscarinic drugs, anti-Parkinsons drugs, and epilepsy drugs.

The risks of this type of medication should be carefully considered by healthcare professionals alongside the benefits when the drugs are prescribed and alternative treatments should be considered where possible.

Prof. Carol Coupland

These findings also highlight the importance of carrying out regular medication reviews.

We found a greater risk for people diagnosed with dementia before the age of 80, which indicates that anticholinergic drugs should be prescribed with caution in middle-aged people as well as in older people, she concludes.

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Long Term Memory Loss Vs Short Term Memory

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Common Causes Of Forgetfulness

Memory slips are aggravating, frustrating, and sometimes worrisome. When they happen more than they should, they can trigger fears of looming dementia or Alzheimers disease. But there are some treatable causes of forgetfulness. Here are six common ones.

Lack of sleep. Not getting enough sleep is perhaps the greatest unappreciated cause of forgetfulness. Too little restful sleep can also lead to mood changes and anxiety, which in turn contribute to problems with memory.

Medications. Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory. As shown in the table below, alternatives are usually available.

Medications that may affect memory and possible substitutes

If you take these drugs

ask about switching to one of these drugs

paroxetine

another antidepressant such as fluoxetine or sertraline , or a different type of antidepressant such as duloxetine or venlafaxine

cimetidine

Underactive thyroid. A faltering thyroid can affect memory . A simple blood test can tell if your thyroid is doing its job properly.

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Anticholinergics: The Anti Drugs

Acetylcholine is the primary neurotransmitter of memory and learning.

When youre low in acetylcholine, you become forgetful and cant concentrate.

You may struggle to find the right words when you speak.

Acetylcholine deficiencies are associated with dementia and Alzheimers medications for these disorders work by preventing the breakdown of acetylcholine in the brain.

” Not all drugs that cause memory loss are prescription medications. Many popular over-the-counter drugs also cause memory loss by blocking the neurotransmitter acetylcholine.

Drugs that block the action of acetylcholine, causing low brain levels of acetylcholine, are known as anticholinergics.

NEED A MENTAL PERFORMANCE LIFT?

Does this sound like you?

Fuzzy thinking, foggy focus, forgetfulness?

Lack of energy and drive?

Struggle to learn and make decisions?

A quality brain supplement can make a big difference.

You can take a look at the list created by The Peoples Pharmacy or download a PDF created by the Indiana University Center for Aging Research.

Not all anticholinergic drugs are equally hazardous, so these lists rate drugs by their level of anticholinergic activity mild, moderate, or severe.

Leo Galland, MD, a renowned functional medicine pioneer, has published an extensive list of anticholinergic substances that includes drugs and herbal remedies.

If your anticholinergic risk is high, we urge you to bring this to your doctors attention.

How Common Is Fainting From Lisinopril

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This is not that common with Lisinopril, but can happen especially if the person is dehydrated or not eating or drinking enough, or is already on other BP medications.

Dr. Sayeedperforms echocardiograms and stress tests at the Midtown Manhattan and Westchester offices at Columbia Doctors. He is also trained in cardiac CT imaging.
Lorra Garrick has been covering medical, fitness and cybersecurity topics for many years, having written thousands of articles for print magazines and websites, including as a ghostwriter. Shes also a former ACE-certified personal trainer.

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A Fluke In The Results And Areas For Future Research

One result that left researchers scratching their heads was the fact that the patients who took drugs that do not cross the blood-brain barrier had better outcomes on attention compared with those who took drugs that cross to the brain. Although cardiovascular disease does negatively affect attention, it is not a sign of dementia. Nation and Jean Ho, PhD, a postdoctoral scholar at the UCI MIND, are pursuing new studies for a better understanding of those results.

For now though, this new research could help pave the way for different prescribing practices that take into account other diseases linked to hypertension.

Alzheimers has been built as a disease of the brain in which nothing else has anything to do with it, says Constantino Iadecola, PhD, the director of the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine, who was not involved in the study. Vascular damage to the brain is caused mainly by high blood pressure. It’s also a major contributor to Alzheimer’s disease. So the message to the community is that if you treat high blood pressure, you also treat Alzheimer’s disease.

Iadecola advises patients to check your blood pressure regularly to get treated as soon as possible. He also advises Black patients in particular who have a tendency toward hypertension to treat high blood pressure now in any shape or form.

Midlife High Blood Pressurea Risk Factor For Cognitive Decline

After decades of observational research, theres general agreement that high blood pressure in middle age is a risk factor for later-life cognitive decline, including overall cognition, memory, and processing speed.

Much of the data comes from studies of large groups of adults who were followed for many years. For example, the NIA-supported Honolulu-Asia Aging Study measured cognition in 3,734 Japanese-American men in Hawaii, with an average age of 78, whod had their blood pressure measured more than 20 years earlier. Researchers found that for every 10-mmHg increase in systolic blood pressure, there was a 9 percent increase in risk for poor cognitive function.

Similarly, the Atherosclerosis Risk in Communities neurocognitive study followed more than 13,000 white and African-American adults, starting at age 48 to 67, for 20 years. In later life, performance on cognitive tests of short-term memory, executive function, and processing speed fell for all participants. Those with high blood pressure or prehypertension at the start of the study scored worse than those with normal blood pressure. Participants who used drugs to treat their high blood pressure scored better than those with untreated hypertension, but not as well as those with normal blood pressure.

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Lisinopril And Liver Damage

As a drug class, ACE inhibitors have been associated with rare cases of acute liver injury, specifically cholestatic liver injury. However, lisinopril is different from other ACE inhibitors in two ways:

  • Apparent liver injury is more common with lisinopril than other ACE inhibitors.
  • The type of liver injury lisinopril causes is hepatocellular, rather than cholestatic.

Both types of liver injury are serious, but hepatocellular liver injury involves liver cell death and can ultimately be fatal. According to the drug labels for Prinivil and Zestril, patients who develop jaundice or drug-induced hepatitis should stop taking the drug and seek help from a medical expert right away.

Many of the lawsuits filed against companies that make drugs containing lisinopril have focused on liver damage. Plaintiffs argue that drugmakers like Merck and AstraZeneca should have done more to warn patients about this potential adverse event.

Icipants And Study Design

Preventing Memory Loss

These analyses use longitudinal data from the Cardiovascular Health Study, a prospective multi-center, population-based cohort study of cardiovascular risk factors in 5,888 community-dwelling older adults. An ancillary study was conducted to evaluate the incidence and prevalence of dementia in a subset of the cohort who had brain magnetic resonance imaging between 1991 and 1994., Participants were evaluated at baseline with clinical assessments including physical, cognitive, and functional assessments as well as laboratory testing. Medication, function, cognitive, physical exam, and medical history data were updated at annual participant visits. For this analysis, participants determined to have prevalent dementia at the time of the MRI were excluded. In order to limit confounding by indication, we also restricted our analyses to participants with treated HTN defined as self-reported HTN and taking an antihypertensive medication. Because ACE inhibitors are also commonly used for congestive heart failure treatment and because heart failure may impair cognition, we further excluded patients with heart failure at baseline. After applying these entry and exclusion criterion, 1054 participants formed our study population .

Sample Population

MRI= brain magnetic resonance imaging CHF= congestive heart failure

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Warning Disclaimer Use For Publication

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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