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Can Molly Permanently Damage Your Brain

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How Long Do The Effects Of Mushrooms Last

MDMA – Respect Your Brain

Psychedelic mushrooms take effect within 20 minutes after theyve been ingested. They can be eaten alone or consumed with other food, or they may be brewed like tea and drank.

Their effects can last for up to 6 hours long enough for intense changes to body and brain chemistry to have harmful effects that can lead to chronic health conditions.

Treatment For Molly Abuse And Addiction

Treating molly abuse and addiction may include a medically supervised detox. During detox, medical professionals may be able to begin to assess the damage caused by molly abuse.

After detox, a substance abuse treatment program can help a person gain insight into the nature of their addiction, and how to achieve and maintain sobriety.

Our helpline is open, and our staff is ready to provide information on addiction treatment options for you or your loved one. Contact us today.

Written by the Addiction Resource Editorial Staff

Addiction Resource aims to provide only the most current, accurate information in regards to addiction and addiction treatment, which means we only reference the most credible sources available.

These include peer-reviewed journals, government entities and academic institutions, and leaders in addiction healthcare and advocacy. Learn more about how we safeguard our content by viewing our editorial policy.

  • Human Psychopharmacology Acute, sub-acute and long-term subjective consequences of ecstasy consumption in 430 regular users

Does Ecstasy Cause Brain Damage Controversial Evidence

Does Ecstasy really cause brain damage? There is a whirlwind of controversy surrounding Ecstasy and trying to determine whether it causes brain damage. Some people claim that the drug can cause significant damage to neurons, axons, and the entire serotonin system within the brain. Others claim that there is no solid scientific evidence to support the claims that Ecstasy causes brain damage. There are respected researchers on both sides of the spectrum some believe that the drug isnt dangerous while others think its use can have significant long term consequences.

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In An Emergency Call For Help

If you suspect an overdose or severe reaction while using ecstasy, dial triple zero to call an ambulance immediately. A quick response can save someones life.

Don’t delay because you think you might get into trouble. Ambulance officers are not obliged to call the police.

Stay with the person until the ambulance arrives. Tell the ambulance officers as much as you can about what drugs were taken, when they were taken and whether the person has a medical condition.

Can Acid Dmt Or Other Psychedelics Cause Brain Damage

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    There has been a great deal of debate around the idea of using psychedelics for the treatment of certain mental health conditions. While initial studies have been encouraging, much remains unknown about the effects of exposing the human brain to such powerful substances. As new frontiers open in the care of mental health, questions like whether acid, DMT, or other psychedelics can cause brain damage will have to be answered first.

    Psychedelic drugs arent known to cause severe overdose or addiction problems. But are they dangerous in other ways? Does LSD kill brain cells? What are the effects of DMT on the brain? Learn more about how psychedelics affect your brain.

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    How Ecstasy Affects The Body

    The effects of ecstasy can vary from person to person and depend on factors such as:

    • the amount and strength of the dose
    • your physical make-up and state of mind
    • how you respond to the drug
    • whether it has been mixed with other drugs.

    Generally, effects begin around 20 minutes and will last around 3-4 hours. They may include:

    • euphoria and feeling energetic and confident
    • accelerated heart rate and breathing
    • rise in blood pressure
    • jaw clenching and teeth grinding
    • tingling skin and muscle aches and pains
    • dilated pupils
    • dilutional hyponatremia when the user ‘drowns’ their brain by drinking too much water.

    Warning Signs Of Brain Damage From Drugs And Alcohol

    If you or a loved one has abused drugs or alcohol for a long period of time, suffered from drug-induced seizures, overdoses, or suspects there may be some brain damage, there are several different warning signs to look for. If you suspect something is wrong or you are experiencing some of these problems, you should always seek medical help.

    These warning signs may indicate short-term or permanent brain damage caused by drug and alcohol abuse.

  • Delayed reactions Delayed reaction times can be a sign that there is a problem with brain function. Examples could include taking a long time to recognize youre touching something hot or raising your hands to block your face after something has already hit you.
  • Severe memory problems Things like memory lapses or blackouts should not be a regular occurrence. If they are, its time to seek medical attention and investigate the potential role of drugs and alcohol on the problem.
  • Hallucinations If a person is hallucinating while they are sober, it could be caused by frequent or long-term drug abuse. Many medical conditions can also cause hallucinations , so its important to see a doctor if you are sensing objects, people, tastes, smells, or bodily movements that arent real.
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    What Are The Effects Of Taking Mdma

    MDMA starts to work about 20 minutes after it is taken and the effects usually last for 3 to 4 hours. It can make people feel euphoric, energetic, confident and very affectionate towards others. People who take a lot or who have a strong batch of MDMA may feel like they are floating or have hallucinations.

    It can also cause unwanted side effects, such as:

    • large pupils

    A serious problem is overheating and becoming dehydrated when using MDMA in hot and humid conditions. People who take MDMA should take regular breaks to cool down, and sip water slowly. Some people have also died by drinking too much water after taking MDMA.

    MDMA overdose can lead to a coma or death. If you think someone has overdosed on MDMA, call triple zero for an ambulance. Ambulance officers dont have to call the police.

    No: Ecstasy Doesnt Cause Brain Damage

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    Some evidence says that using ecstasy is unlikely to cause any sort of brain damage. One study compared illicit ecstasy users and non-users and excluded individuals with lifetime exposure to illicit drugs and alcohol. This was done with 52 illicit ecstasy users and 59 non-users among ages 18 to 45.

    The study findings by Halpern et al. found very little evidence of decreased cognitive performance in ecstasy users. These researchers suggest that there may not be as much evidence of neurotoxicity as previously thought. With that said, they did state that further research needs to be conducted.

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    Brain Disorders Caused By Drug And Alcohol Abuse

    Many drugs have harmful neurological effects that impact the brains ability to function and maintain its health.3 Whether the drugs cause seizure, stroke, or have direct effects on the cells in the brain, the results can have lasting effects on a persons health and quality of life.

    According to the Substance Abuse and Mental Health Services Administration , there are several different brain disorders that can be caused by drug and alcohol abuse.4

    • Inhalants11

    How Large Of A Dose Would Be Neurotoxic In Humans

    Unfortunately, we dont really know. George Ricaurte, the main US-government funded researcher studying MDMA neurotoxicity, has claimed that even a small recreational dose of MDMA could be neurotoxic. Other researchers have given human volunteers moderate doses of MDMA with before-and-after brain scans, and could find no signs of damage. Doses of MDMA that produce neurotoxicity in lab animals have generally been considerably higher than a human user would normally take, but smaller animals are also usually more resistant to drug toxicity than humans.

    As a result, just because a given dosage doesnt appear to cause damage to a rat or monkeys brain doesnt necessarily mean that dosage is safe for humans. In 2002, the US governments Food and Drug Administration granted approval for using MDMA on human volunteers at recreational dosage levels, which suggests that the governments medical experts do not believe there is a significant risk of harm from a few moderate doses of MDMA under controlled circumstances with medical supervision.

    Although there is considerable debate over how much MDMA it would take to cause damage to a human users brain, there is no real doubt that at some dosages damage can and will occur. Fortunately, brain damage doesnt seem to happen at moderate recreational doses.

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    Reversing Brain Damage Caused By Mdma

    The brain is a complex organ that helps to determine the quality of an individuals life. Using MDMA can negatively affect the brain in a number of ways. Heres the good news: the brain can rewire itself. Treatment programs like ours can help reverse some, if not all, of the negative brain changes that MDMA causes.

    Contact us today if you or someone you know has been negatively affected by MDMA. Our brain-focused treatment programs can help individuals recover and live a thriving, purposeful life.

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    Is It Possible To Reverse Brain Damage From Drugs

    MDMA Metabolism in the Body: How MDMA Affects the Brain ...

    Some types of brain damage from drugs are reversible, not all are. If you or a loved one has suffered brain damage due to drug abuse, its impossible to say what is repairable and what is not purely based on symptoms or diagnosis.

    A medical doctor will be able to tell you how much of the damage can be reversed if any. While large amounts of cellular death in the brain is not repairable, early-stage brain damage may be repairable.

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    What Causes Mdma Neurotoxicity

    Scientists arent sure yet. What we do know is that some chemical gets into the serotonin axons through the SERotonin Transporters , tiny molecular pumps that neurons use to collect serotonin. Once inside, this chemical is broken down by an enzyme. This breakdown process creates oxidizing chemicals that can damage the neuron. We arent sure what that first mystery chemical is. For a long time, we thought it was probably dopamine, which we knew played a role in neurotoxicity However, more recent research has discovered that dopamines main role in promoting MDMA neurotoxicity is by increasing body temperature: significant overheating is a very important factor in whether or not MDMA neurotoxicity will occur.

    As far as what the actual toxic chemical might be, there are several theories. The most popular theory is that a hepatic metabolite of MDMA is to blame. Another theory suggests that MDMA itself may be the toxic chemical, since there is evidence that MDMA itself may be broken down in the brain.

    Do Psychedelics Cause Brain Damage

    Other potential, if uncommon, health problems occur when DMT induces serotonin syndrome. DMT has a chemically similar structure to the serotonin neurotransmitter, and when the body accumulates too much serotonin, the patient usually experiences symptoms such as agitation, confusion, loss of muscle coordination, and high blood pressure.

    Serotonin syndrome tends to occur in patients who are taking antidepressants and may already have elevated levels of serotonin as a result. If untreated, serotonin syndrome can get quite severe and lead to seizures, an irregular heartbeat, a loss of consciousness, and death.

    As with other psychedelics, DMT can exacerbate pre-existing mental health conditions, but it is unlikely to be the impetus behind the development of psychological problems in people who were not primed for them. The little research conducted on DMT suggests that it is not a habit-forming substance, but as with any drug, there are risks that frequent use might lead users down the road of psychological dependence on it.

    Unlike other psychedelics, DMT use does not induce tolerance .

    A health blog on CNN answered the user-submitted question of whether acid causes permanent brain damage by saying that if people who have used psychedelics do not have occasional flashbacks, and do not develop hallucinogen persisting perception disorder, then there is little chance that the DMT use has harmed the brain.

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    Does Mdma Make Holes In Your Brain

    Not that we know of. This popular but apparently incorrect idea came from a pair of PET scans shown on the Oprah TV show one from a normal patients brain, and the other from an emotionally troubled girl who had used a number of drugs

    This is the normal brain.

    As you can see, there are visual holes in the girls PET scan. However, these dont represent literal holes in her brain rather, they are areas where there was relatively low blood flow or sugar consumption Its a very strange brain scan, but theres no way to know what caused this effect or whether its the result of damage or something temporary

    MDMA does have some effects on blood flow in your brain, both while you are high and for several weeks afterwards However, studies of blood flow in users brains havent found lasting changes. When researchers gave human volunteers brain scans to examine blood flow, gave them recreational doses of MDMA, and performed follow-up brain scans for several weeks they found that there was somewhat reduced blood flow in their brains after use, but blood flow returned completely to normal within 3-4 weeks

    At the end of the day.

    For more detailed information and research on MDMA neurotoxicity, visit Erowid.org.

    Recognizing An Ecstasy High

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    When someone is using ecstasy, they exhibit some clear signs of drug use that are easy to spot if you know what youre looking for. Behavioral changes and physical changes can both be signs of an ecstasy addiction. If you believe that someone you care about may be abusing ecstasy, monitor their behavior for signs of use and misuse. Along with the side effects listed above, you might notice additional physical and mental effects, such as:

    • Lethargy or fatigue
    • Susceptibility to getting the common flu or cold
    • Hemorrhaging
    • Psychosis
    • Cardiovascular collapse

    If you notice one or more of these symptoms, its possible that your loved one is abusing ecstasy regularly or even suffering from an addiction to the drug. Early intervention is the best way to avoid long-term effects from the drug, so its important to get them help. As a drug that causes direct chemical changes to the pathways in the brain, there are many dangers surrounding ecstasy use.

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    The Psychological Impact Of Psychedelic Mushrooms

    The main effects of shrooms are psychological, often associated with literally expanding consciousness. However, the dramatic changes to brain state and neuron interactions can trigger long-lasting and even chronic effects. One of the most frightening effects is intense panic and paranoia. People who abuse mushrooms may experience a panic attack, feel like they are being watched, or have a break from reality that leads them to display psychotic symptoms. They may harm themselves or others with violent outbursts. They may end up in the hospital with lasting damage from accidental harm during a psychotic episode.

    Psychosis induced by psilocybin is very similar to symptoms of schizophrenia, and someone who is at risk for developing schizophrenia may trigger this mental condition by abusing psychedelic drugs. The intense changes to brain chemistry may make some conditions like anxiety or bipolar disorders worse however, magic mushrooms have been associated, in some very small medical studies, with reduced depression. Persistent psychosis is characterized by:

    • Visual disturbances

    Does Ecstasy Cause Memory Loss

    Yes, MDMA can cause memory loss. One study found that MDMA caused memory loss in ecstasy users, aged 17 to 31, who used the drug an average of 2.4 times a month. All study subjects stopped taking the drug for two weeks , so measurements of mental function would be accurate.

    In the end, results showed that ecstasy users memories had declined over the years, particularly the areas of memory associated with recalling new memories. Users vocabulary, their ability to remember names, and their ability to remember how to get from one place to another were also affected.1

    In another study on Molly drug abuse and memory loss, 23 new users were compared to 43 people who didnt use any illicit drugs aside from cannabis. The study ran for 3 years, with 12-month check-ups. On average, the participants of the study who used ecstasy took 33 pills in one year. The results concluded that new ecstasy users who took 10 or more Molly tablets in their first year showed a decline in their immediate and long-term memory.2

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    Is Ecstasy Neurotoxic

    Much of the research suggests that Ecstasy is neurotoxic, but the neurotoxic effects may be prevented if it is used therapeutically, in a controlled setting, at a low dose. However, we do not know with 100% certainty that these effects can be prevented. All active doses of the drug are likely going to lead to oxidative stress within the brain. The pharmacokinetics of MDMA imply that even small increases in a dose could lead to large changes in plasma MDMA levels which could have a neurotoxic effect.

    Various types of pharmacological agents such as: antioxidants, SSRIs, and 5-HTP injections have been shown to have a slight neuroprotective effect in rodent MDMA studies. With that said, the rodents that experienced neuroprotection typically receive injections of high doses of these protective agents this may produce a more potent protective effect in rodents than humans.

    Research conducted by Liechti in 2000 showed that pretreatment with 40 mg of an SSRI can decrease MDMA effects by 1.5 mg/kg. In 1999, Aguirre found that 2x daily administration of high dose alpha-lipoic acid completely blocked the neurotoxicity of Ecstasy in rats. Some even hypothesize that antioxidants even help enhance recovery from low doses of MDMA.

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