Vitamin B12 And Hypothyroidism
Before we move on, if you see a term or phrase that you dont really understand, check out our frequency asked questions series found on Common Thyroid Questions and Answers.
OK, back to the topic.
Many hypothyroid patients are deficient in some vitamins and minerals, including vitamin B12.
One study enrolled 116 hypothyroid patients who were evaluated for signs and symptoms of vitamin B12 deficiency.
Scientists discovered that 46 or 39.6% participants had low levels of this micronutrient.
The prevalence of vitamin B12 deficiency was equal in both men and women.
Based on the discovery that about 40% of hypothyroid patients are deficient in this vitamin, scientists emphasized the importance of screening people with hypothyroidism for vitamin B12 levels. Replacement of vitamin B12 leads to improvement of symptoms patients experience.
In addition, evidence shows that pernicious anemia affects hypothyroid patients 20 times more frequently than other people. Pernicious anemia is a condition that occurs when the body doesnt absorb sufficient amount of cobalamin.
This form of anemia is called pernicious due to the fact it was considered a deadly disease back in time. The primary reason why pernicious anemia was deadly in the past was due to the lack of adequate treatment.
Nowadays, it is possible to treat and manage this condition with vitamin B12 injections and supplements.
Are You At Risk Of Vitamin B12 Deficiency
There are many causes for vitamin B12 deficiency. Surprisingly, two of them are practices often undertaken to improve health: a vegetarian diet and weight-loss surgery.
Plants dont make vitamin B12. The only foods that deliver it are meat, eggs, poultry, dairy products, and other foods from animals. Strict vegetarians and vegans are at high risk for developing a B12 deficiency if they dont eat grains that have been fortified with the vitamin or take a vitamin supplement. People who have weight-loss surgery are also more likely to be low in vitamin B12 because the operation interferes with the bodys ability to extract vitamin B12 from food.
Conditions that interfere with nutrient absorption, such celiac or Crohns disease, can cause B12trouble. So can the use of commonly prescribed heartburn drugs, which reduce acid production in the stomach . The condition is more likely to occur in older people due to the cutback in stomach acid production that often occurs with aging.
It May Help Ease Insomnia
Given its perceived ability to treat anxiety, stress, and depression, gotu kola may also be used to treat the insomnia that sometimes accompanies these conditions. Some consider this herbal remedy to be a safe alternative to prescription medications used to treat insomnia and other sleep disorders.
How to use: Take 300 to 680 mg of gotu kola extract 3 times per day for up to 14 days at a time.
2013 review , gotu kola can reduce the appearance of stretch marks. Its thought that the terpenoids found in gotu kola increase collagen production in the body. This may help prevent new stretch marks from forming, as well as help heal any existing marks.
How to use: Apply a topical cream containing 1 percent gotu kola extract to the affected area several times per day.
How to do a skin patch test: Its important to do a patch test before using any topical medication. To do this, rub a dime-sized amount on to the inside of your forearm. If you dont experience any irritation or inflammation within 24 hours, it should be safe to use elsewhere.
Researchers in a 2015 study on rats found that wound dressing containing gotu kola had healing effects on multiple types of wounds. This includes clean cuts by sharp objects, irregular tears caused by blunt-force trauma, and infected tissue.
More research is needed to expand upon these findings.
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How Does Vitamin D Deficiency Affect Your Memory And Mood
Are you getting enough vitamin D? If youre like mostpeople, you probably arent. Vitamin D deficiencies are becoming more common,affecting about half of the people on planet Earth. According to one study, 70%of adults and 67% of kids ages 1-11 have insufficient levels of vitamin D. Itsno wonder when you consider the increasing amount of time we spend indoors andall that sunscreen we slather on our bodies when were outside.
Vitamin D deficiency, or even just less-than-optimal levels of the sunshine vitamin, can spell trouble for your memory and moods. Low levels of vitamin D have been associated with depression, Alzheimers disease and other dementias, and cognitive decline, as well as psychosis, autism, heart disease, and about 200 other conditions.
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What Are The Disadvantages Of Injecting Vitamin B12 Ampoules
Headache, itching, and swelling of the skin, stomach pain, heartburn, diarrhea, joint pain, and nerve pain
In rare cases: irregular breathing, palpitations, chest pain, sudden weight gain, muscle weakness and pain, muscle cramps, excessive thirst, excessive urination, leg pain, dizziness, numbness, burning sensation when swallowing, Coughing, Shortness of breath, severe fatigue, swelling of the hands, thighs, legs and ankles and redness, pain and heat in one leg, redness of the skin and pimples.
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Does Folic Acid And B12 Reduce The Risk Of Memory Loss
Although some early observational studies have suggested that vitamin B12 and folic acid supplements may reduce the risk of memory loss and improve cognitive performance, new study results in the journal Neurology say it isnt so.
Two-year folic acid and vitamin B12 supplementation did not beneficially affect performance on 4 cognitive domains in elderly people with elevated homocysteine levels, says study author Rosalie Dhonukshe-Rutten, PhD, of Wageningen University in the Netherlands. It may slightly slow the rate of decline of global cognition, but the small difference reported may be attributable to chance._____________________________________________________________________________________________________________________________________________________________
Vitamin B12 Therapy That’s Easy to Swallow_____________________________________________________________________________________________________________________________________________________________
Dhonukshe-Rutten and her colleagues conducted a double-blind, randomized, placebo-controlled trial to look at the effects of 2-year folic acid and vitamin B12 supplementation on cognitive performance in elderly people with elevated levels of homocysteine. High levels of this amino acid have been linked to memory loss and Alzheimers disease.
Dhonukshe-Rutten and her colleagues look forward to discovering more about how B-vitamins interact with the brain as they continue their research in this area.
Bonus: Nutrients For The Brain
Theres no doubt the ones above are the best vitamins for brain memory and concentration, but theres more that can help you.
Here are other types of nutrients that can nourish your command center, as well as helpful brain health vitamins you may need:
- Omega-3 fatty acids such as EPA and DHA are necessary for the formation and survival of cell membranes of the brain cells. The best sources are salmon, fish oils, and nuts.
- Magnesium is a mineral that helps reduce anxiety symptoms, migraine headaches, and brain fog. This is why its also a significant nutrient for people with thyroid problems.
- Coenzyme Q10 or CoQ10 may prevent or reduce the risks of neurodegenerative diseases by maintaining the function of the mitochondria, the powerhouse of the cells. Excellent sources are oranges, strawberries, and super greens.
These brain vitamins can help you take care of your nervous system, as well. Note, though, you still need to see your doctor before you increase your intake of these vitamins.
Its essential you dont go overboard or become deficient to avoid health problems. How much you need depends on factors such as age, medical history, present diseases, and health risks.
While supplements can help increase your vitamin levels, getting them from healthy foods is still the better way.
What kinds of brain vitamins are you taking? Share your list in the comments section below!
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Choosing The Best Vitamin B12 Supplement
Its almost always preferable to get your nutrition from food rather than supplements if possible, but vitamin B12 might be an exception.
For those with compromised digestive systems, supplemental B12 is better absorbed than B12 from food where its bound to protein.
And for some, the ability to absorb vitamin B12 from dietary supplements is limited by how much intrinsic factor is present.
There are a lot of options when choosing a B12 supplement.
Besides being available in the usual tablets, capsules, and liquid drops, it is also available in sublingual tablets, sprays, or lozenges.
Youll also find several forms of B12 in supplements cyanocobalamin, methylcobalamin, and hydroxocobalamin.
There seems to be little difference in absorption or bioavailability for most people.
However, hydroxocobalamin is recommended for anyone with the MTHFR genetic mutation.
It is also the form usually used in B12 injections for treating deficiency.
Strange but true: No plants or animals can synthesize vitamin B12. It can be made only by microorganisms like bacteria and fungi. Even synthetic vitamin B12 supplements require bacteria for production.
Can Children Also Be Deficient In Vitamin B12
B12 deficiency is serious in infants and can cause symptoms such as anemia, movement problems, and developmental problems that can be dangerous. This Vitamin deficiency is rare in children but is more common in children whose mothers did not eat enough animal products during pregnancy or whose mothers were vegetarians. B12 supplements can be helpful for mothers as well as B12 fortified foods during pregnancy and lactation.
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What Vitamin B12 Cant Do
The Internet is full of articles lauding the use of vitamin B12 to prevent Alzheimers disease, heart disease, and other chronic conditions or reverse infertility, fatigue, eczema, and a long list of other health problems. Most are based on poor or faulty evidence.
Take Alzheimers disease as an example. Although there is a relationship between low vitamin B12 levels and cognitive decline, clinical studiesincluding those involving people with Alzheimers diseasehave not shown improvement in cognitive function, even doses of the vitamin as high as 1000 micrograms.
For now, its best to get enough vitamin B12 to prevent a deficiency, and not look to it as a remedy for what ails you.
May Improve Heart Health By Decreasing Homocysteine
High blood levels of the common amino acid homocysteine have been linked to an increased risk of heart disease.
If youre significantly deficient in vitamin B12, your homocysteine levels become elevated.
Studies have shown that vitamin B12 helps decrease homocysteine levels, which may reduce your risk of heart disease (
Therefore, further research is needed to understand the relationship between vitamin B12 and heart health.
Vitamin B12 can decrease blood homocysteine, a type of amino acid that is associated with an increased risk of heart disease. However, research does not currently support the claim that vitamin B12 reduces this risk.
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Why Do People Take Vitamin B
Vitamin B-12 has been looked at as a treatment for many diseases and conditions. These include fatigue, Alzheimer’s disease, heart disease, breast cancer, high cholesterol, and sickle cell disease. However, the results have been inconclusive. Studies suggest that vitamin B-12 does not help with stroke risk or lung cancer.
Vitamin B-12 supplements do help people who have a deficiency. Low levels of vitamin B-12 are more likely in people over age 50. Vitamin B-12 is also more common in those with certain conditions, like digestive problems and some types of anemia. Low vitamin B-12 can cause fatigue, weakness, memory loss, and other problems with the nervous system.
A recent study showed that vitamin B-12, used with folic acid and vitamin B6, reduces the risk for age-related macular degeneration in women with heart disease or multiple risk factors for heart disease.
Absorption Of B12 In Older Adults
As we age, we begin to slow down in more ways than one. Organ function becomes less efficient, a consequence that extends to the stomach. As many as 30% of older adults develop a condition called atrophic gastritis, or achlorhydria. This condition means that the stomach secretes less acid with which to digest food. Without gastric acid, B12 is not able to separate from R-factor and bind to IF for absorption, preventing B12 absorption despite sufficient dietary intake. To analogize, the B12 you ate cant get off the bus , as it drives past the exit for the airport and misses its flight from the digestive system into the blood.
Elderly populations also manifest a lifetime of damage and immune and organ decline that leads to decreased B12 absorption. The specific health issues that contribute to low B12 status include intestinal inflammation, autoimmune disorders that prevent the production of B12 carrier proteins, damage to the wall of the intestine, hostile gut organism overgrowth, pernicious anemia, and certain medications.
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Signs And Symptoms Of Vitamin B12 Deficiency
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Vitamin B12, also known as cobalamin, is an important water-soluble vitamin .
It plays an essential role in the production of your red blood cells and DNA, as well as the proper functioning of your nervous system.
Vitamin B12 is naturally found in animal foods, including meats, fish, poultry, eggs and dairy. However, it can also be found in products fortified with B12, such as some varieties of bread and plant-based milk.
Unfortunately, B12 deficiency is common, especially in the elderly. Youre at risk of deficiency if you dont get enough from your diet or arent able to absorb enough from the food you eat.
- Those whove had surgery that removes the part of the bowel that absorbs B12
- People on the drug metformin for diabetes
- People following a strict vegan diet
- Those taking long-term antacid drugs for heartburn
Unfortunately, symptoms of a vitamin B12 deficiency can take years to show up, and diagnosing it can be complex. A B12 deficiency can sometimes be mistaken for a folate deficiency.
Low levels of B12 cause your folate levels to drop. However, if you have a B12 deficiency, correcting low folate levels may simply mask the deficiency and fail to fix the underlying problem (
Here are 9 signs and symptoms of a true vitamin B12 deficiency.
May Give You An Energy Boost
Vitamin B12 supplements have long been touted as the go-to product for a surge of energy.
All B vitamins play an important role in your bodys energy production, though they dont necessarily provide energy themselves .
Currently, there is no scientific evidence to suggest that vitamin B12 supplements can boost energy in those with sufficient levels of this vitamin .
On the other hand, if youre significantly deficient in vitamin B12, taking a supplement or increasing your intake will likely improve your energy level .
In fact, one of the most common early signs of vitamin B12 deficiency is fatigue or lack of energy.
Vitamin B12 is involved in energy production in your body. Taking a supplement may improve your energy level, but only if youre deficient in this vitamin.
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Learn Which Vitamins And Supplements Can Help Support Sharp Cognitive Function Aid Memory And Improve Concentration
When were young, we rely on concentration to get good grades in school, and our memory helps us retain information when the time comes to take a test. As we get older, we continue to rely on memory and concentration to achieve new goals. Finishing college, taking on a new job, and learning new hobbies all require these essential cognitive functions to keep performing. Without our memories, who are we?
Yet with age, the vitamins and minerals vital to our cognitive health naturally begin to decline in our bodies. So what can we do? Remember that a healthy diet and lifestyle begins with nutritious food and regular activity. According to the Mayo Clinic, studies suggest that the Mediterranean diet – rich in healthy fats from olive oil and fish – may help reduce the risk of mild cognitive impairment.
Evaluating The Epidemiologic Evidence
Even while there is a general impression of strong epidemiologic evidence to support associations between the B-vitamins and cognitive decline, in actuality, the evidence is weak. The impression may be driven by the numerous cross-sectional and case-control studies that relate dietary or biochemical levels of the B-vitamins to cognition or disease status. A primary limitation of these types of studies is that one cannot determine whether the observed association is a cause or effect of the disease. For example, both serum and dietary intake levels of folate have been reported to decline with prolonged institutionalization , and duration of dementia . In addition, studies that use a one-time cognitive assessment cannot separate attained or lifetime cognitive ability from cognitive decline due to age or disease. Confounding bias is highly likely in these types of studies because cognitive ability is related to many factors, including education, socio-economic status, and healthy lifestyle behaviors. Depression may be another source of confounding in these studies, as it is a common condition in persons with dementia , and has been associated with folate deficiency .
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These Symptoms Indicate A Deficiency Of Vitamin B12
The main symptoms are weakness, fatigue, weakness of the body, loss of appetite, irritability, tingling, stiffness, hair loss, mouth ulcers, constipation, memory loss, excessive stress, headache, shortness of breath, yellowing of the skin, eyesight. . If this happens to you, consult an expert immediately.
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Aging Or B12 Vitamin Deficiency
Aging or B12 Deficiency is a topic that has become a serious concern especially for those over age 60. Sally M. Pacholok R. N. authored of a book about this common B12 Vitamin deficiency. She says that in her work as a nurse she saw many patients with missed diagnoses of this particular vitamin deficiency including some who had been diagnosed with age related dementia and others who had to be rushed to the emergency room for care.
She finally teamed up with Jerffrey J. Stuart, D. O. to write a book on the topic, Could It Be B12? An Epidemic of Misdiagnoses
Symptoms that could be the result of either Aging or B12 Deficiency
- Mental confusion, memory loss, irritability, apathy, sleepiness, personality changes, depression, hallucinations,violent behavior. Not all of these are seen in each case but any of them could be symptoms.
- Abnormal sensations eg, pain, tingling, numbness, diminished sense of touch or temperature, clumsiness, tremor, weakness, incontinence, vision changes, damage to the optic nerve
- TIAs , stroke, coronary artery disease, congestive heart failure, palpitations, bloodclots, low blood pressure when standing up sometimes causes falls or fainting.
- chronic fatigue, loss of appetite, gastrointestinal problems, osteoporosis, tinnitus, prematurely grey hair
Symptoms that could be the result of Aging or B12 deficiency
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