Thursday, September 29, 2022

Why Does Uti Affect The Brain

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Findings Shed Additional Light On The ‘why Now’ Question About What Triggers A Stroke

How playing an instrument benefits your brain – Anita Collins

Using the New York State Inpatient Databases and Emergency Department Databases from 2006 to 2013, researchers identified hospital and emergency room visits for stroke and infections. Types of infections included skin, urinary tract, septicemia , abdominal, and respiratory. Researchers then compared hospitalizations for infections for 7, 14, 30, 60, 90, and 120 days before the strokes occurred. Risk was estimated for each infection type by comparing the group with infections to a control group during the same period.

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Every infection type was found to be linked with an increased likelihood of ischemic stroke. The greatest association was with urinary tract infection, which was associated with a five times greater risk for stroke within the 7-day window and a three times greater risk within 30 days of the infection. For all infection types, the association with stroke decreased over time after the infection, adding support to the theory that the potential for infection to trigger a stroke is greatest over a shorter time window, according to researchers.

Researchers divided hemorrhagic stroke into two categories, intracerebral hemorrhage, caused by a ruptured blood vessel in the brain, and subarachnoid hemorrhage, a stroke that happens when the inner lining of the brain bleeds.

Do Urinary Tract Infections Cause Personality Changes

Suddenly, moms forgetfulness has turned into full blown dementia-like symptoms. What would cause her personality to change overnight? Could this be because she has a Urinary Tract Infection ?

Sudden personality and/or behavioral changes and urinary tract infections are conditions that are very common among the elderly. Conclusive evidence hasnt shown how urinary Tract Infections affect memory. But, there have been reports, like this one ,where doctors have describe a cessation of personality changes after treatment for a UTI.

An explanation describing a cause-and-effect relationship between the two conditions however, according to research literature, is still not clear. The fact remains however, that personality changes and UTIs frequently occur together in the elderly.

How do you get prepared for such a scenario ?

In the tips below discuss possible signs your loved one may have a UTI and what you can do to help so the situation does not escalate.

Why Are Seniors Susceptible To Utis

Older individuals are vulnerable to UTIs for several reasons. The biggest culprit is an immune system weakened by time that increases susceptibility to any infection. Also, the elderly may have a diminished ability to take care of themselves. Reduced cognitive abilities and lower energy levels are issues that cause decreased hygiene and increased bacteria in seniors too. Becoming less communicative, often due to the same diminished cognitive capabilities, can be a contributing factor as well.

Urine overstaying its welcome in the bladder is common in elderly populations, and can foster bacteria that spreads and turns into a UTI. There are several reasons this may occur. One is that seniors may lower fluid intake during the day to avoid the embarrassment and inconvenience caused by bladder control issues. This leads to less frequent urination and a pool of urine being held in the bladder much longer. Also, aging men and women undergo a gradual weakening of the muscles of the bladder and pelvic floor, or a prolapsed bladder, leading them to retain more urine and to experience incontinence.

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How Do You Get Sepsis From A Uti

Untreated urinary tract infections may spread to the kidney, causing more pain and illness. It can also cause sepsis. The term urosepsis is usually used to describe sepsis caused by a UTI. Sometimes incorrectly called blood poisoning, sepsis is the bodys often deadly response to infection or injury.

Senior Home Care Services

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Centric Healthcare offers a wide range of specialized short-term and long-term senior home care services developed to meet the unique care needs of seniors while protecting their dignity. We work with you to create a customized care plan for you or your loved one. The care plan can be designed to address UTI risk factors and encourage preventive behaviors. Services are provided in-home, avoiding the infection risks associated with care facilities, nursing homes, and similar communal living arrangements.

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Older Adults Should Have Other Symptoms Too

When your loved ones doctor suspects a UTI, be sure to mention whether these symptoms are also present:

  • Fever over 100.5 °F
  • Worsening urinary frequency or urgency
  • Sudden pain with urination
  • Tenderness in the lower abdomen, above the pubic bone

Having at least two of the symptoms above, along with a positive urine culture, will confirm a UTI.

Side And Suprapubic Pain

Pain during urination is on the list of typical UTI symptoms, but other types of pain often arent mentioned because theyre less common. An uncomplicated urinary tract infection may cause mild to moderate suprapubic pain, a type of pain that most patients experience as a feeling of pressure or discomfort just above the public bone.

You may also experience a more generalized pelvic pain or cramping in your abdomen. Short-lived pelvic pain may occur during your infection. It can also turn into chronic pain after the infection clears up.

When your infection travels from the bladder to your kidneys, you can develop flank pain, or pain thats felt in your side. Flank pain arises as the infection causes swelling in the kidneys. When that happens, youll experience a steady, aching pain.

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Other Symptoms Of Utis

If the person has a sudden and unexplained change in their behaviour, such as increased confusion, agitation, or withdrawal, this may be because of a UTI.

These pages explain what a UTI is, the different types of UTIs, their symptoms and treatments, and gives tips on how they may be prevented.

Brain Signaling And Microglial Activation

Urinary Tract Infections (UTIs) – Symptoms & Treatment – Dr. Robert Matthews

Microglial activation may represent one of the earliest changes observed in sepsis-associated encephalopathy and prolonged microglial activation may negatively affect other brain cells . Early microglial activation in sepsis was evidenced in mice models within 4 hours following LPS injection, as assessed by the increased proinflammatory cytokine IL1 level in microglia . Using Positron Emission Tomography imaging in nonhuman primates, another study demonstrated microglia activation only 1h after LPS-induced systemic inflammation . Moreover, experimental studies suggest that aging may increase the intensity of microglial activation and the production proinflammatory cytokines in the hippocampus, notably IL1 . The IL1-mediated inflammatory process in the hippocampus was confirmed in different models of systemic inflammation, including cecal ligation and puncture and peripheral surgery . Numerous experimental studies suggest that these proinflammatory mediators released in the central nervous system at the onset of sepsis will in turn lead to neuronal loss within vulnerable areas of the brain, including the hippocampus . Collectively, these findings represent a neuropathological basis for persistent cognitive impairment, hippocampal atrophy, and electroencephalographic changes observed in sepsis survivors .

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Causes Of Encephalopathy Requiring Specific Treatment

Standard laboratory tests should be performed systematically to detect and correct common metabolic disturbances that can cause delirium or coma . In addition to sedatives and analgesics, many classes of drugs currently administered in critically ill patients can induce acute brain dysfunction, notably a number of antibiotics, steroids, and cardiac drugs .

What Happens If A Uti Goes Untreated For A Week

The main danger associated with untreated UTIs is that the infection may spread from the bladder to one or both kidneys. When bacteria attack the kidneys, they can cause damage that will permanently reduce kidney function. In people who already have kidney problems, this can raise the risk of kidney failure.

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As Well As Your Focus And Concentration

You might have heard of post-nut clarity a situation where your brain suddenly feels focused after you have an orgasm.

Indeed, many people find that masturbating helps them concentrate better. As such, they might masturbate before working, studying, or taking a test.

Theres no scientific explanation for this, as it hasnt been studied specifically. However, this sense of clarity and focus might be a result of feeling relaxed and happy after an orgasm.

While oxytocin is commonly known as the love hormone and associated with social bonding, its also associated with de-stressing and relaxation.

As one 2005 study points out, oxytocin plays an important role in regulating stress and reducing anxiety.

It does this by reducing blood pressure and lowering your cortisol levels. Cortisol is a hormone associated with stress.

So, if youre hoping to relieve some tension after a tough day at work, masturbating might be a good relaxation technique!

Ischemic Stroke Versus Hemorrhagic Stroke: Whats The Difference


Every year, more than 795,000 people in the United States have a stroke, according to the Centers for Disease Control and Prevention , and about 140,000 strokes result in death every year. There are two main types of stroke: ischemic stroke, which is caused by blood clots, and hemorrhagic stroke, caused by bleeding around the brain. About 87 percent of strokes are ischemic.

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Bjhwupslc: Rev: Solid: 16

You were visiting your mom and she seemed very confused and disoriented. She claimed the retirement home had moved her to a different apartment and she didnt know why.

Fortunately, you knew the reason for her confusion was not to be ignored because you had seen this out-of-sorts behavior before. Your mom hadnt been moved to a new apartment, but she probably had another urinary tract infection.

According to Washington University Clinical Associates primary care specialist Chelsea Pearson, MD, Family and caregivers are key in helping us identify infection in older adults. When you notice a sudden change in behavior- even a subtle one- you want to take it seriously.

Falls, agitation, confusion, changes in appetite, and incontinence in someone who was previously able to get to the bathroom can all be signs of a urinary tract infection or UTI.

When an older woman has a UTI, the symptoms are different from a younger woman. There might not be any painful burning during urination always a typical sign. This is because as you get older, your immune response changes its part of normal aging.

A UTI places stress on the body, says Dr. Pearson, and any type of stress, physical or emotional, can cause an older adult to become confused. For those suffering from Alzheimers disease or dementia, a UTI can make dementia temporarily worse.

You want to keep your urine clear by drinking four to six 8-ounce glasses of water a day.

Can Elderly Recover From Delirium

Recovering from Delirium Delirium can last from a day to sometimes months. If the persons medical problems get better, they may be able to go home before their delirium goes away. Some peoples delirium symptoms get much better when they go home.

Delirium is most often caused by physical or mental illness and is usually temporary and reversible.

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Insulin Regulates Brain Function But How Does It Get There


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  • Sarah M. Gray, Rick I. Meijer, Eugene J. Barrett Insulin Regulates Brain Function, but How Does It Get There?. Diabetes 1 December 2014 63 : 39923997.

    We have learned over the last several decades that the brain is an important target for insulin action. Insulin in the central nervous system affects feeding behavior and body energy stores, the metabolism of glucose and fats in the liver and adipose, and various aspects of memory and cognition. Insulin may even influence the development or progression of Alzheimer disease. Yet, a number of seemingly simple questions are unanswered. Here we briefly review accumulated findings affirming the importance of insulin as a CNS regulatory peptide, examine the current understanding of how peripheral insulin is delivered to the brain, and identify key gaps in the current understanding of this process.

    Controlling Risk Factors To Prevent Stroke

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    While this research on the association of infection with stroke risk is interesting, infection doesnt rival some of the more well-known risk factors just yet, says Bahouth. Those include high blood pressure, high cholesterol, diabetes, atrial fibrillation, smoking, poor diet, and low exercise, she says. Taking the appropriate medicines, not smoking, exercising, and eating a healthy diet can all help reduce those risks, says Bahouth.

    Using commonsense measures like good handwashing techniques and extra precautions when youre around people who are ill can help you avoid infection, she says.

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    If you do get sick with an infection, drinking a lot of water to prevent the dehydration that comes with infections is good idea, says Bahouth. We know that when a person is dehydrated it affects the blood vessel wall, and that creates lots of opportunity for the blood to get thicker and for the platelets to clot together, she says.

    Be aware that some over-the-counter cold medications can increase blood pressure, which can be an additional risk for people who are prone to high blood pressure, says Bahouth. If you have high blood pressure, talk to your pharmacist or healthcare provider about your condition so they may recommend an OTC symptom-relieving medication that’s safe for you, she says.

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    Infections Especially Utis May Trigger Strokes

    HealthDay Reporter

    THURSDAY, June 27, 2019 — A urinary tract infection might be more than just a painful nuisance for some, with new research suggesting it could raise the risk of stroke in vulnerable people.

    The study of over 190,000 stroke patients found that the risk of suffering a stroke was heightened in the weeks and months following any infection that required a trip to the hospital. But urinary tract infections showed the strongest link.

    People were over five times more likely to suffer an ischemic stroke in the week following a UTI, versus the year before the infection, the findings showed.

    Ischemic strokes — the most common type of stroke — are caused by a blood clot that diminishes blood flow to the brain.

    The researchers said the findings do not implicate milder infections that people manage at home.

    “We’re probably capturing more-severe infections with this study,” said senior researcher Dr. Mandip Dhamoon, an associate professor of neurology at Mount Sinai’s Icahn School of Medicine, in New York City.

    The study cannot prove that infections actually triggered strokes. But based on past research, Dhamoon said, it is biologically plausible: Infections can increase body-wide inflammation and may contribute to blood clots.

    There are a lot of unknowns, though — including whether certain treatments can not only clear a patient’s infection, but also reduce the risk of a subsequent stroke. That’s a question for future studies, Dhamoon said.

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    How Is A Uti Diagnosed In A Person With Delirium

    Making a UTI diagnosis in a person with delirium is not always straightforward.

    As we already mentioned, delirium may be the only noticeable symptom of a UTI in older adults. This is because it can be hard to tell if adults who are bedbound or have dementia are having pain with urination or having to urinate more often. They may not be able to communicate their symptoms. Or if they wear diapers for incontinence , its hard to tell how often they urinate.

    But healthcare providers are trained to look carefully for infection and other underlying causes in any person who experiences sudden confusion.

    A healthcare provider will usually start by doing a thorough physical exam and asking the person or their caretaker about their symptoms. In some cases, a fever, smelly urine, or blood in the urine can be a helpful clue.

    The diagnosis of delirium is made based on specific criteria, like making sure the change in mental status has occurred over a short amount of time, and that these changes are different from how the person usually acts. So, if someone who has dementia is usually calm most of the time but all of a sudden becomes violent, this may mean they are experiencing delirium.

    To confirm a diagnosis of delirium, the provider will look for a cause. Not everyone with delirium has an infection, which could be due to medications or exposure to a toxic substance. Tests can help with this process, including:

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    What Causes Utis In The Elderly

    Anything that introduces bacteria into the urinary tract or impedes the flow of urine and causes urine to stay in the bladder is very likely to cause a UTI.

    Eighty five percent of all UTI infections are caused by Escherichia coli or E. coli bacteria. Several other types of bacteria make up the other fifteen percent, but E.coli is by far the most prominent, and it can make its way into the urinary tract several different ways.

    E. coli is found naturally where digestion occurs in the gastrointestinal tract, so it can sneak into the urinary tract. This commonly happens because the end of the gastrointestinal tract is the anus, and the beginning of the urinary tract is the urethra. The anus and the urethra are close to one another, especially on the female body.

    Due to the proximity of the entry and exit of the above two pathways, poor hygiene can cause UTIs. Back-to-front wiping after a bowel movement can transfer bacteria into the urethra. Wearing soiled underwear or disposable undergarments too long can also introduce bacteria into the urinary tract. Bacteria in both cases is an infectious traveler that multiplies.

    How Long Does Uti Induced Dementia Last

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    You may notice some of the following symptoms start to display in your loved one, signaling a change in mental state. The most important thing to remember about the link between UTI and dementia is that the behavior change is significant and happens fairly quickly, usually over a period of one to two days.

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